Changes

*'''Silicon Valley ''' - Several computer technology companies emerged in this part of California in the late 1990s. This led to an abundance of opportunities for entrepreneurs to form their own startup companies. This exponential increase in startups subsequently led to numerous venture capital firms moving to Silicon Valley. More and more startups and VC firms continued to move into Silicon Valley, creating the innovative "cluster" in the area. With the help of nearby research institutions and universities, particularly Stanford University and the University of California at Berkeley, Silicon Valley blossomed into one of the premiere innovative concentrations in the world.

*'''Route 128 ''' - Influenced by academia, industry, and government, Boston's Route 128 has become a prime geographical area for entrepreneurship and innovation. With the resources available at nearby institutions like Harvard College and The Massachusetts Institute of Technology, as well as through the federal funding given to encourage innovation and research, Route 128 has become one of the most prolific clusters for innovation and policy in the country.

*'''Research Triangle Park ''' - The Research Triangle of North Carolina was formed to take advantage of three of the state's big universities, UNC Chapel Hill, NC State, and Duke, to create a zone in North Carolina where startups, research, and innovation all thrive. This triangle allows for startups to be immediately put in an area with the resources and support to succeed as well as the opportunities for research needed to thrive.

*'''Confluence Water Technology Innovation Cluster ''' - Ohio, Northern Kentucky, and Southeast Indiana have obtained support from the EPA and SBA to collaborate to establish the Ohio River Valley region as a global leader in innovation by attracting the best entrepreneurs and innovators and by creating and attracting jobs and investment.